Why the world’s most talked-about skin treatment isn’t as strange as it sounds
When headlines started shouting about celebrities getting the so-called “salmon-sperm facial”, it caught everyone’s attention. From Hollywood red carpets to glossy magazine features, this unusual-sounding treatment has become one of the hottest trends in advanced skincare. But what exactly is behind the buzz, and is it really worth trying?
At MyAesthetics in Manchester, we’re here to cut through the noise, explain the science, and show you why this treatment – known properly as polynucleotide therapy – could be one of the most effective ways to restore, repair, and rejuvenate your skin.
What is the “salmon-sperm facial”?
Despite the name, the treatment does not involve facials with salmon fish. Instead, it uses polynucleotides, which are chains of molecules (DNA fragments) often derived from salmon DNA. These molecules are almost identical to human DNA, making them safe, biocompatible, and highly effective in stimulating the skin’s natural repair processes.
The nickname “salmon-sperm facial” comes from the fact that early formulations used salmon DNA sourced from sperm cells. Today, polynucleotide products are purified, tested, and produced under strict medical-grade standards, so they are completely safe.
Why are celebrities raving about it?
From K-pop stars to Hollywood actors, many high-profile figures credit polynucleotide treatments for their glowing, youthful complexions. The appeal lies in the fact that polynucleotides don’t just mask ageing – they address the root causes of skin decline.
Here’s why celebs love it:
- True regeneration: Stimulates fibroblasts to produce collagen and elastin.
- Improved skin quality: Targets pigmentation, fine lines, and dullness.
- Natural-looking results: No frozen or overfilled appearance.
- Fast recovery: Minimal downtime compared to lasers or aggressive peels.
For celebrities constantly in front of the camera, treatments that deliver real improvement without downtime are priceless.
The science behind polynucleotides
So how do polynucleotides actually work?
- Cell repair and regeneration -Polynucleotides bind to cell receptors, triggering processes that repair damaged tissue.
- Boosting hydration – They increase hyaluronic acid production in the skin, keeping it plump and hydrated.
- Anti-inflammatory action – Calm redness and irritation, making it ideal for sensitive skin.
- Antioxidant defence – Protects against free radical damage from pollution, stress, and UV exposure.
This makes them particularly effective for under-eye darkness, fine lines, acne scars, and general skin laxity.
What happens during a polynucleotide facial?
At MyAesthetics Manchester, your treatment journey begins with a consultation and Aura Skin Scanner analysis. This allows us to see beyond the surface and tailor the treatment to your needs.
A typical session includes:
- Cleansing and prep – the skin is ready.
- Microinjections of polynucleotides – Delivered directly where regeneration is needed (often under the eyes, cheeks, or around the mouth).
- Soothing post-care – To calm the skin and accelerate healing.
Patients often report a slight stinging sensation, but discomfort is minimal.
Who is it for?
The polynucleotide “salmon-sperm facial” is suitable for both men and women seeking subtle, natural rejuvenation. It’s particularly beneficial if you are noticing:
- Under-eye dark circles and hollowness
- Fine lines and wrinkles
- Skin laxity and thinning
- Acne scars or uneven texture
- General dullness or lack of radiance
For patients aged 35-75, this treatment fits perfectly into an “ageing well” approach, restoring skin quality without altering your natural features.
How does it compare to fillers or wrinkle reducers?
Unlike wrinkle-relaxing injections or dermal fillers, polynucleotides don’t add volume or freeze muscles. Instead, they work beneath the surface to repair, hydrate, and stimulate long-term skin health.
This makes them ideal for patients who:
- Want a natural look without obvious signs of treatment.
- Are not suitable for tear-trough filler but still want to improve under-eye darkness.
- Prefer regenerative, evidence-based skin health solutions.
Why choose MyAesthetics for your treatment?
Opening in October 2025, MyAesthetics Manchester is set to become the city’s new hub for advanced, natural aesthetics. Here’s why we’re different:
- Unique AI facial scanner to track your skin journey with real before-and-after evidence.
- Exclusive use of Galderma products and cutting-edge polynucleotide therapies.
- A wellness-inspired clinic space designed for comfort, trust, and results.
Whether you’re curious about the “salmon-sperm facial” or looking to future-proof your skin with regenerative medicine, we’re here to guide you with honesty and expertise.
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👉 Learn about polynucleotide therapy
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To book your first consultation, visit MyAesthetics Clinics or contact the team directly on
+44 161 524 8035 | info@myaestheticsclinics-yfgd.temp-dns.com.
FAQs: Salmon-Sperm Facial (Polynucleotides)
Is the salmon-sperm facial safe?
Yes. Modern formulations are purified, medical-grade, and undergo rigorous safety testing.
How many sessions do I need?
Most patients see results after 2-3 sessions, spaced a few weeks apart, with top-ups recommended every 6-12 months.
Is there downtime?
Mild redness or swelling may occur for 24-48 hours, but downtime is minimal.
Does it hurt?
There may be mild discomfort during injections, but numbing options are available.
When will I see results?
Improvements in hydration and glow can be seen within days, with collagen stimulation developing over weeks.
